Blog Post: The Impact of Age on Intra Cervical Insemination with Donor Sperm
Intra Cervical Insemination (ICI) with donor sperm has become an increasingly popular option for couples and individuals looking to start a family. It is a relatively simple and non-invasive procedure that involves injecting washed and concentrated sperm directly into the cervix, increasing the chances of fertilization. While ICI has proven to be a successful method for many, there are certain factors that can impact its success rate, one of them being the age of the person receiving the sperm.
Age has long been known to play a significant role in fertility, and this is no different when it comes to ICI with donor sperm. In this blog post, we will explore the impact of age on ICI with donor sperm and how age can affect the chances of successful conception.
Impact on Egg Quality
The age of the person receiving the sperm can have a direct impact on the quality of their eggs. As women age, the number and quality of their eggs decrease, making it more challenging to conceive. This decline in egg quality can affect the success rate of ICI with donor sperm, as the quality of the egg is crucial in the fertilization process.
According to a study published in the Journal of Assisted Reproduction and Genetics, the chances of conception through ICI decrease significantly for women over the age of 35. The study found that in women aged 35 and above, the success rate of ICI was only 8.3%, compared to 17.6% in women under the age of 35.
Impact on Sperm Quality
While the age of the person receiving the sperm can impact the success rate of ICI, the age of the sperm donor can also play a role. As men age, the quality of their sperm can decrease, which can affect the chances of fertilization. This decline in sperm quality can be attributed to factors such as lifestyle choices, environmental factors, and genetic predisposition.

The Impact of Age on Intra Cervical Insemination with Donor Sperm
A study published in the Journal of Andrology found that the chances of successful ICI decrease when using sperm from older donors. The study found that sperm from donors over the age of 40 had a lower motility rate, meaning they were less likely to reach and fertilize the egg. This can result in lower success rates for ICI with donor sperm from older donors.
Impact on Hormonal Levels
Age can also impact the hormonal levels of the person receiving the sperm, which can affect the success rate of ICI. As women age, their hormone levels can fluctuate, making it more challenging to predict ovulation and the best time for ICI. This can result in missed opportunities for conception and lower success rates.
According to a study published in the Journal of Assisted Reproduction and Genetics, hormonal levels in women above the age of 35 were found to be significantly different compared to those under 35. These hormonal changes can make it more challenging to conceive through ICI, and the study found that the success rate was only 9.4% for women over 35, compared to 16.2% for women under 35.
Impact on Pregnancy Complications
Age can also play a role in the risk of pregnancy complications for women undergoing ICI with donor sperm. As women age, they are more likely to experience complications such as gestational diabetes, preeclampsia, and preterm labor. These complications can not only affect the health of the mother but also the success of the pregnancy.
A study published in the Journal of Obstetrics and Gynecology found that women over the age of 35 who conceived through ICI were more likely to experience pregnancy complications compared to younger women. The study also found that the risk of cesarean delivery was higher for women over 35, which can also impact the success of the pregnancy.
Summary:
Intra Cervical Insemination with donor sperm has become a popular method for couples and individuals looking to start a family. However, age can significantly impact the success rate of ICI. As women age, the quality of their eggs and hormonal levels decrease, making it more challenging to conceive. The age of the sperm donor can also play a role, as older donors may have lower sperm quality. Additionally, age can increase the risk of pregnancy complications, which can affect the success of the pregnancy. It is essential to consider these factors and consult with a fertility specialist when considering ICI with donor sperm.








